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Updated: Feb 9, 2026

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贝克林1-BCL2自调节复合物的破坏促进了小鼠的长寿

Álvaro F Fernández1,2, Salwa Sebti1,2, Yongjie Wei1,2,3

  • 1Center for Autophagy Research, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Nature
|June 1, 2018
PubMed
概括

通过破坏贝克林1-BCL2相互作用,增加自延长了小鼠的寿命并改善了健康寿命. 这一发现为促进哺乳动物长寿和预防与年龄相关的疾病提供了新的途径.

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