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Updated: Feb 9, 2026

A Fluorescence-based Assay of Phospholipid Scramblase Activity
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在高胆固醇症小鼠中,氧化脂具有前炎性和前动脉性作用

Xuchu Que1, Ming-Yow Hung1,2,3, Calvin Yeang1

  • 1Department of Medicine, University of California, San Diego, La Jolla, CA, USA.

Nature
|June 8, 2018
PubMed
概括

氧化脂 (OxPL) 导致炎症和动脉样硬化. 一种新的抗体片段 (E06-scFv) 在小鼠中中和了OxPL,显著减少了动脉样硬化,大动脉膜疾病和全身炎症,同时延长了寿命.

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