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Updated: Feb 9, 2026

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反同型亲和成熟改善人类B细胞对重复性表位的反应

Katharina Imkeller1,2, Stephen W Scally3, Alexandre Bosch3

  • 1B Cell Immunology, German Cancer Research Institute, Heidelberg, Germany.

Science (New York, N.Y.)
|June 9, 2018
PubMed
概括

这项研究揭示了像疟疾寄生虫的环体蛋白 (PfCSP) 这样的重复性抗原如何增强抗体保护. 同型抗体相互作用改善B细胞激活和抗体亲和力,帮助病原体防御.

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