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Updated: Feb 9, 2026

The ChroP Approach Combines ChIP and Mass Spectrometry to Dissect Locus-specific Proteomic Landscapes of Chromatin
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The ChroP Approach Combines ChIP and Mass Spectrometry to Dissect Locus-specific Proteomic Landscapes of Chromatin

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准备含有局部特异性DNA修饰的染色体的插即用方法:染色体结构对基因切割修复的影响

Deb Ranjan Banerjee1, Charles E Deckard1, Meagan B Elinski1

  • 1Department of Chemistry , Texas A&M University , College Station , Texas 77843 , United States.

Journal of the American Chemical Society
|June 9, 2018
PubMed
概括

研究人员开发了一种用于研究DNA修复的设计染色体的新方法. 这种技术揭示了染色质结构如何影响基切除修复 (BER) 的效率,根据病变位置和染色质紧缩而显示显著的抑制或加速.

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