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在淋巴瘤中控制瘤信号的多蛋白超级复合体

James D Phelan1, Ryan M Young1, Daniel E Webster1

  • 1Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Nature
|June 22, 2018
PubMed
概括

一个新发现的My-T-BCR超级复合体驱动瘤性B细胞受体 (BCR) 在扩散性大B细胞淋巴瘤 (DLBCL) 中发出信号. 这种超级复杂性解释了对ibrutinib的反应,并指导DLBCL亚型的向治疗.

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