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Updated: Feb 8, 2026

Specificity Analysis of Protein Lysine Methyltransferases Using SPOT Peptide Arrays
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通过使用Corynebacterium diphtheriae的Pilin聚合排序酶通过特定的lysine-isopeptide键标记蛋白质

Scott A McConnell1, Brendan R Amer1, John Muroski1

  • 1Department of Chemistry and Biochemistry, UCLA-DOE Institute for Genomics and Proteomics and the Molecular Biology Institute , University of California, Los Angeles , Los Angeles , California 90095 , United States.

Journal of the American Chemical Society
|June 22, 2018
PubMed
概括

研究人员开发了一种新的酶,CdSrtA3M,用于特定位点的蛋白质修饰. 这种酶有效地产生 lysine-isopeptide 键,使得用于治疗和诊断的高级蛋白质生物结合成为可能.

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