Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

64.7K
Overview
64.7K
Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

9.6K
Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
9.6K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

3.0K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
3.0K
Physical Methods for Controlling Microbial Growth: Radiation and Filtration01:26

Physical Methods for Controlling Microbial Growth: Radiation and Filtration

1.7K
Radiation and filtration are essential tools for microbial control, targeting microorganisms through distinct mechanisms. Radiation eliminates microbes by damaging their DNA, either killing them or inhibiting their growth. Based on wavelength, radiation is classified into two types: nonionizing and ionizing radiation.Non-ionizing radiation, such as UV radiation (200–400 nm), is absorbed by DNA, causing defects that effectively disinfect surfaces, air, and water, including safety cabinets.
1.7K
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

55
The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more...
55
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

24
Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
24

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Facile generation of <i>Hermes</i> insertion mutants in prototrophic <i>Candida glabrata</i> for use in nutrient-limited environments.

Microbiology spectrum·2026
Same author

Assessment of Outcomes of Rehabilitation Program for Socially At-Risk Patients.

Southern medical journal·2026
Same author

A Mechanism Driving Echinocandin Heteroresistance in <i>Candida glabrata</i>.

bioRxiv : the preprint server for biology·2026
Same author

Disruption of Lam Family Sterol Transporters Results in Sporulation Defects in the Yeast <i>Saccharomyces cerevisiae</i>.

Biochemistry. Biokhimiia·2026
Same author

Limited genome evolution of <i>Cryptococcus neoformans</i> following an accidental infection in the research laboratory.

ASM case reports·2026
Same author

The heat-ramp method to study regulated cell death in a pathogenic yeast <i>Cryptococcus neoformans</i>.

bioRxiv : the preprint server for biology·2026

相关实验视频

Updated: May 1, 2026

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
06:32

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Published on: September 19, 2016

9.8K

关于"消毒肺部免疫力依赖于向类似真菌亡的细胞死亡"的评论

Abdel Aouacheria1, Kyle W Cunningham2, J Marie Hardwick3

  • 1ISEM, Institut des Sciences de l'Evolution de Montpellier, Université de Montpellier, CNRS, EPHE, IRD, Montpellier, France.

Science (New York, N.Y.)
|June 23, 2018
PubMed
概括
此摘要是机器生成的。

这种真菌可能不会经历由人类中性粒细胞触发的细胞死亡. 目前的证据不足以证实蛋白酶信号或真菌酶抑制剂

更多相关视频

Alveolar Macrophage Phagocytosis and Bacteria Clearance in Mice
11:20

Alveolar Macrophage Phagocytosis and Bacteria Clearance in Mice

Published on: March 2, 2019

11.1K
Opsonophagocytic Killing Assay to Assess Immunological Responses Against Bacterial Pathogens
08:47

Opsonophagocytic Killing Assay to Assess Immunological Responses Against Bacterial Pathogens

Published on: April 5, 2019

12.4K

相关实验视频

Last Updated: May 1, 2026

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
06:32

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Published on: September 19, 2016

9.8K
Alveolar Macrophage Phagocytosis and Bacteria Clearance in Mice
11:20

Alveolar Macrophage Phagocytosis and Bacteria Clearance in Mice

Published on: March 2, 2019

11.1K
Opsonophagocytic Killing Assay to Assess Immunological Responses Against Bacterial Pathogens
08:47

Opsonophagocytic Killing Assay to Assess Immunological Responses Against Bacterial Pathogens

Published on: April 5, 2019

12.4K

科学领域:

  • 菌群学
  • 免疫学
  • 细胞生物学

背景情况:

  • 菌是一种常见的真菌,会导致人类的菌.
  • 已知肺中性粒细胞会引发真菌病原体的细胞死亡.
  • 之前的研究表明,A. fumigatus的细胞死亡是依赖于酶的.

研究的目的:

  • 在与肺中性粒细胞相互作用时研究Aspergillus fumigatus细胞死亡的机制.
  • 要确定真菌细胞死亡是否由蛋白酶信号级联介导.
  • 评估一种同类于人类生存的真菌酶抑制剂的作用.

主要方法:

  • 这项研究由Shlezinger等人进行. 使用特定技术观察真菌细胞死亡.
  • 分析的重点是酶依赖的途径和蛋白质酶信号传递.
  • 研究一种真菌酶抑制剂的作用.

主要成果:

  • 这项研究报告说,Aspergillus fumigatus经历了酶依赖的细胞死亡.
  • 这种细胞死亡是由肺中性粒细胞触发的.
  • 然而,菌酶抑制剂阻碍蛋白酶信号级联的证据被发现是不可靠的.

结论:

  • 这些发现质疑先前报告的菌细胞死亡机制.
  • 需要进一步的研究来证实蛋白酶信号传递和真菌酶抑制剂在A. fumigatus病变中的作用.
  • 可靠的技术对于准确调查真菌与宿主相互作用至关重要.