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Updated: Aug 11, 2026

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
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Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes

Published on: May 31, 2018

瘤亡因子和巨细胞分泌的因子菌素的身份

B Beutler, D Greenwald, J D Hulmes

    Nature
    |August 8, 1985
    PubMed
    概括

    巨细胞分泌卡切丁,一种抑制脂蛋白脂酶 (LPL) 活性的激素,在感染期间导致高甘油三血症. 卡切丁与瘤死因子 (TNF) 具有结构和功能上的相似之处.

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    Phagocytosis of Apoptotic Cells01:17

    Phagocytosis of Apoptotic Cells

    Cells undergoing apoptosis form apoptotic bodies that must be removed immediately to prevent inflammation, autoimmune diseases, and necrosis. Phagocytosis is carried out by professional phagocytes such as macrophages or  immature dendritic cells. Non-professional phagocytes such as  epithelial cells and fibroblasts also take part in this process; however, they are not as effective as professional phagocytes. 
    Normal cells contain receptors that prevent them from being recognized by phagocytes.