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Updated: Feb 8, 2026

Preparation of High-Temperature Sample Grids for Cryo-EM
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一种必不可少的Plasmodium vivax入侵复合物的冷EM结构

Jakub Gruszczyk1, Rick K Huang2, Li-Jin Chan1,3

  • 1The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.

Nature
|June 29, 2018
PubMed
概括

通过向P. vivax网细胞结合蛋白2b (PvRBP2b) 与转移素受体1 (TfR1) 的相互作用来阻止疟疾寄生虫的入侵. 结构洞察力显示了疫苗开发的结合部位.

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Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular architecture, tracks for intracellular transport, positioning of organelles, assembly of cilia and flagella. They mediate the bipolar spindle assembly for chromosomal segregation and positioning of the cell division plate in dividing cells. The formation of microtubule complex structures depends on the cell type, cell stage, and cell function.
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