古代山羊基因组揭示了肥沃半月地区的马赛克化
Kevin G Daly1, Pierpaolo Maisano Delser1,2, Victoria E Mullin1,3
1Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.
概括
养山羊不是单一的事件,而是涉及到近东地区养的多个野生山羊来源. 这导致了不同的早期山羊种群,形成了现代山羊遗传学,并显示了早期人类对牛奶生产等特征的选择.
科学领域:
- 古代基因组学
- 古遗传学
- 动物养
背景情况:
- 目前关于山羊养的遗传证据对于单一或多个起源是不确定的.
- 了解山羊养的起源是追踪人类和动物之间早期互动和农业发展的关键.
研究的目的:
- 通过使用古老的DNA来研究山羊化的遗传历史.
- 要确定山羊的化是单一事件,还是来自不同野生山羊群体的多次事件.
- 确定早期人类对养山羊的选择压力.
主要方法:
- 从古石器到中世纪时期的83只古山羊生成和分析基因组数据.
- 在51个古老的山羊样本中使用全基因组测序.
- 将古代山羊基因组进行比较,以了解种群结构和进化历史.
主要成果:
- 证明了山羊的化涉及多个不同的古老野山羊来源.
- 确定了分散的化过程,导致遗传和地理上不同的新石器时代山羊种群.
- 显示了这些早期种群对亚洲,非洲和欧洲现代山羊品种的差异贡献.
- 检测了包括色素,身材,繁殖和牛奶生产在内的特征的早期人工选择.
结论:
- 养山羊是一个复杂的,多区域的过程,涉及不同的野生祖先.
- 早期养的山羊群体表现出人类对重要的农业特征的遗传特征.
- 这项研究提供了8000年前人类对关键动物物种基因组的影响的证据.
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