使用扩展的遗传密码和帕拉介导的化学去保护

Jun Liu1, Feng Zheng2, Rujin Cheng3

  • 1University of California, San Francisco , Department of Pharmaceutical Chemistry , 555 Mission Bay Boulevard South , San Francisco , California 94158 , United States.

概括

研究人员开发了一种使用正交tRNA和催化剂将特定位点的类固醇 (Sec) 纳入蛋白质的新方法. 这一突破使得蛋白的有效生产成为可能,并促进了蛋白质工程和功能研究.

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