中枢神经回路的演变是Drosophila伴侣偏好的基础
Laura F Seeholzer1, Max Seppo1, David L Stern2
1Laboratory of Neurophysiology and Behavior, The Rockefeller University, New York, NY, USA.
Nature
|July 12, 2018
概括
特定物种的求爱依赖于激素的处理. 神经回路的差异,而不是检测,导致Drosophila melanogaster和Drosophila simulans的雄性对相同的费洛蒙产生相反的反应,导致生殖隔离.
科学领域:
- 神经伦理学
- 进化生物学
- 化学生态学
背景情况:
- 求爱仪式对于维持近亲物种的繁殖隔离至关重要.
- 费洛蒙在特定物种的求爱行为和伴侣识别中起着重要作用.
研究的目的:
- 调查素7,11-heptacosadiene如何在雄性Drosophila melanogaster和Drosophila simulans中引起相反的求爱反应.
- 识别基底的神经机制物种特异性费洛蒙感知和行为输出.
主要方法:
- 在雄性D. melanogaster和D. simulans中检测和信号处理的比较分析.
- 电生理学记录和神经电路映射来追踪费罗蒙信号通路.
- 行为测试以评估对特定费洛蒙的求爱反应.
主要成果:
- 这两种物种的雄性用相似的外围感官神经元检测7,11-heptacosadiene.
- 费洛蒙信号对中枢神经元 (P1神经元) 的差异传播控制了求爱行为.
- 在神经激发和抑制的平衡中发生的转变使激素的效果从吸引力转变为排斥力.
结论:
- 尽管保留了外围检测机制,但特定物种的激素反应可以通过中枢神经回路的变化演变.
- 神经通路的多样化可以灵活地适应对环境线索的行为反应.
- 这项研究强调了神经电路可塑性在生殖隔离和行为分歧的演变中的作用.
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