视觉投影神经元调解了Drosophila中的定向求爱
Inês M A Ribeiro1, Michael Drews2, Armin Bahl2
1Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA; Max Plank Institute of Neurobiology, Am Klopferspitz 18, 82152 Martinsried, Germany; Institute of Molecular Pathology, Campus-Vienna-Biocenter 1, 1030 Vienna, Austria.
Cell
|July 24, 2018
概括
男果的视觉神经元对于求爱至关重要. 沉默这些神经元会损害导向和歌声, 而激活它们会引发求爱行为.
科学领域:
- 神经科学
- 动物的行为
- 感官系统
背景情况:
- 视力对于许多动物来说至关重要,
- 在Drosophila的求爱中,雄性使用视觉线索来定位,追逐和唱歌.
研究的目的:
- 研究LC10视觉投影神经元在Drosophila雄性求爱行为中的作用.
- 确定LC10神经元如何处理与求爱相关的视觉信息.
主要方法:
- 在雄性Drosophila中抑制和单方面激活LC10神经元.
- 行为测试以评估方向性,近距离维护和求爱歌曲.
- 电生理记录以描述LC10神经元对运动的反应.
主要成果:
- 沉默LC10神经元破坏了男性的方向性,接近女性,
- 通过基于运动的中心-周围机制,LC10神经元对小型移动物体表现出偏好的反应.
- 单边的LC10激活模仿女性引起的方向和翅膀延伸, 由求爱兴奋增强.
结论:
- LC10视觉投射神经元对于传递Drosophila求爱关键的视觉信息至关重要.
- 这些神经元在整合视觉刺激与求爱回路和兴奋状态方面发挥着关键作用.
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