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Updated: Feb 7, 2026

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
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转移性前列腺癌的基因组特征和结构变异

David A Quigley1, Ha X Dang2, Shuang G Zhao3

  • 1Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco, CA, USA; Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, USA.

Cell
|July 24, 2018
PubMed
概括

转移性前列腺癌的全基因组结构变异揭示了疾病进展的新驱动因素. 这些包括在雄激素受体 (AR) 附近的增强剂放大,以及特定变体与DNA修复缺陷之间的联系.

关键词:
一个BRCA2受体受体抗割的前列腺癌染色体基因融合基因组学发生转移结构变化双重复制全基因组测序

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