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循环素依赖性激酶12是内脏病的药物点

Susan Wyllie1, Michael Thomas1, Stephen Patterson1

  • 1Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, UK.

Nature
|July 27, 2018
PubMed
概括

针对CRK12的新抗莱什曼病药物显示出有前途. 一种基于pyrazolopyrimidine的化合物在临床前模型中是有效的,为内脏leishmaniasis提供了潜在的新治疗方法.

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