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Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
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用DNA功能化染料装载的聚合物纳米粒子:用于扩大核酸检测的超明亮FRET平台

Nina Melnychuk1, Andrey S Klymchenko1

  • 1Laboratoire de Bioimagerie et Pathologies, UMR 7021 CNRS, Faculté de Pharmacie , Université de Strasbourg , Strasbourg CS 60024 , France.

Journal of the American Chemical Society
|August 2, 2018
PubMed
概括

研究人员开发了用于增强光学生物传感的新型纳米粒子探测器. 这些探测器使用采光纳米天线和福斯特共振能量转移 (FRET) 来实现75倍的信号放大,大大提高了核酸的检测极限.

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