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外体PD-L1有助于免疫抑制,并与抗PD-1反应相关

Gang Chen1, Alexander C Huang2, Wei Zhang1,3

  • 1Department of Biology, School of Arts & Sciences, University of Pennsylvania, Philadelphia, PA, USA.

Nature
|August 10, 2018
PubMed
概括

转移性黑色素瘤释放带有编程死亡配体1 (PD-L1) 的外体,抑制T细胞. 循环中的PD- L1水平预测了患者对抗PD- 1治疗的反应.

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