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Updated: Feb 6, 2026

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages
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阿尔法激酶1是细菌ADP-肝素的细胞原性免疫受体

Ping Zhou1, Yang She1,2,3, Na Dong4

  • 1National Institute of Biological Sciences, Beijing, China.

Nature
|August 17, 2018
PubMed
概括

研究人员确定ADP-β-D-曼诺-肝素 (ADP-Hep) 是一种激活NF-κB信号的细菌代谢物. 这一发现揭示了α-酶1 (ALPK1) 作为对宿主防御细菌感染至关重要的模式识别受体.

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