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In vivo Imaging of Transgenic Leishmania Parasites in a Live Host
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莱什曼病

Sakib Burza1, Simon L Croft2, Marleen Boelaert3

  • 1Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK; Department of Public Health, Institute of Tropical Medicine, Antwerp, Belgium; Médecins Sans Frontières, Delhi, India.

Lancet (London, England)
|August 22, 2018
PubMed
概括
此摘要是机器生成的。

莱什曼病是一种被忽视的热带疾病, 虽然在某些地区取得了进展,但冲突和流离失所事件的增加仍在持续,这凸显了对新的控制工具和治疗方法的迫切需要.

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科学领域:

  • 热带医学
  • 感染性疾病
  • 公共卫生

背景情况:

  • 莱什曼病是一种与贫困相关的寄生病,
  • 它呈现为内脏莱什曼病 (VL) 和皮肤莱什曼病 (CL),每年影响0.7-100万人.
  • 世界卫生组织将莱什曼病列为首要被忽视的热带疾病.

研究的目的:

  • 总结一下目前全球莱什曼病的情况.
  • 突出疾病控制方面的挑战和需要新的干预措施.

主要方法:

  • 全球雷什曼病例数据和趋势的审查.
  • 影响疾病传播和控制因素的分析.

主要成果:

  • 由于诊断,治疗和病媒控制的改善,亚洲报告的脊髓炎病例有所减少.
  • 东非继续报告持续存在的VL病例.
  • 冲突和流离失所导致全球LCD病例激增.

结论:

  • 尽管在某些领域取得了进展,
  • 显著的证据缺口和对新工具的需求对于最终控制至关重要.
  • 迫切需要新的治疗方法和控制策略.