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Updated: Feb 6, 2026

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling
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Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling

Published on: March 20, 2018

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使用共价探针对癌症酶活动的CT成像显示了尺寸依赖的模式

Darya Tsvirkun1, Yael Ben-Nun1, Emmanuelle Merquiol1

  • 1The Institute for Drug Research, The School of Pharmacy, The Faculty of Medicine, Campus Ein Karem , The Hebrew University , Jerusalem 9112001 , Israel.

Journal of the American Chemical Society
|August 28, 2018
PubMed
概括

这项研究引入了基于金纳米粒子活动的新型探针 (GNP-ABPs),用于使用计算机断层扫描 (CT) 增强癌症成像. 这些探针能够对瘤中的酶活性进行敏感检测,从而提升功能CT成像能力.

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