活体转化聚合物中继结合的转化
Liangbing Fu1, Tianqi Zhang1, Guanyao Fu1
1School of Chemistry and Biochemistry , Georgia Institute of Technology , 901 Atlantic Drive NW , Atlanta , Georgia 30332 , United States.
Journal of the American Chemical Society
|August 31, 2018
概括
我们开发了一种新的方法,使用一种新的基因导向反应直接连接聚合物. 这种高效的技术简化了复杂的聚合物材料的创建,用于先进的应用.
科学领域:
- 聚合物化学 聚合物化学
- 有机合成 有机合成
- 材料科学 材料科学 材料科学
背景情况:
- 大分子的共价合对于先进的材料和生化应用至关重要.
- 现有的聚合物合和功能化方法在效率和化学选择性方面面临挑战.
- 开发新的结合策略对于现代化学和生物学至关重要.
研究的目的:
- 介绍一种用于生物聚合物的直接结合的新策略.
- 为了使聚合物与小分子和其他合成大分子的合.
- 建立一种高度化学选择性和高效的结合方法.
主要方法:
- 使用环开放型元解聚合 (ROMP) 制备活体聚合物.
- 引入终端基因作为分子内反应的指导组.
- 采用基准稳定的 enyne 图案,以便轻松引入功能目标.
- 利用一种化学选择性继电器合机制.
主要成果:
- 证明了活体聚合物的直接结合到小分子和宏分子.
- 使用基因导向策略实现了快速和高度化学选择性的继电器结合.
- 在环开放转化聚合过程中与各种单体家族的兼容性得到证实.
- 展示了向各种目标引入enyne图案的容易性.
结论:
- 开发的基因定向继电器结合为构建复杂的宏分子系统提供了一种简化方法.
- 这种方法绕过了对专用设备的需求,使得先进的聚合物合成更容易获得.
- 该战略具有设计新型先进材料和与生物系统接口的巨大潜力.
相关概念视频
Polymers
41.0K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
41.0K
Directional Relays
620
Directional relays, essential for managing unidirectional fault currents, enhance the safety and efficiency of power systems. On power lines equipped with directional relays, faults downstream (to the right) of the current transformer typically cause the fault current to lag the bus voltage by approximately 90 degrees, known as the forward direction. In contrast, upstream (left-side) faults may result in the fault current leading the bus voltage by nearly 90 degrees, termed the reverse...
620
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)
2.2K
Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
2.2K
Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)
3.2K
Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...
3.2K
Overcurrent Relays
545
Overcurrent relays, crucial for circuit protection, are connected to the secondary current of a current transformer. There are two primary types of overcurrent relays: instantaneous and time-delay.
Instantaneous overcurrent relays activate immediately when the input current exceeds a predetermined value, known as the pickup current, instantly energizing the circuit breaker trip coil. This rapid response is vital for addressing severe faults quickly.
Time-delay overcurrent relays, on the other...
Instantaneous overcurrent relays activate immediately when the input current exceeds a predetermined value, known as the pickup current, instantly energizing the circuit breaker trip coil. This rapid response is vital for addressing severe faults quickly.
Time-delay overcurrent relays, on the other...
545
Differential Relays
776
Differential relays are used to protect generators, buses, and transformers by comparing electrical quantities at different points. When a fault occurs, the difference in current between the two points triggers the relay to operate, opening the circuit breaker. Under normal conditions, the current entering (i1) and leaving (i2) a generator are equal. When a fault occurs, however, these currents become unequal, and the difference current flows in the relay operating coil, causing the relay to...
776


