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Substrate Generation for Endonucleases of CRISPR/Cas Systems
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Published on: September 8, 2012

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发现广泛存在的I型和V型CRISPR-Cas抑制剂

Nicole D Marino1, Jenny Y Zhang1, Adair L Borges1

  • 1Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA.

Science (New York, N.Y.)
|September 8, 2018
PubMed
概括

研究人员发现了12种新的抗CRISPR (Acr) 基因,包括类型V-A CRISPR- Cas系统的抑制剂. AcrVA1广泛抑制了Cas12a酶,为生物技术提供了新的工具.

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