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一个学会抑制运动的声学后果的皮质过器
David M Schneider1,2, Janani Sundararajan1, Richard Mooney3
1Department of Neurobiology, Duke University School of Medicine, Durham, NC, USA.
Nature
|September 14, 2018
概括
鼠标学会使用一种新的声学虚拟现实系统来抑制其运动中的可预测的声音. 这种经验增强了它们检测新声音的能力,
科学领域:
- 神经科学
- 听觉感知
- 传感动力集成
背景情况:
- 预测与运动相关的声音对于听力至关重要.
- 大多数人不知道神经回路是如何抑制这些声音的.
研究的目的:
- 研究神经机制来抑制反应的声音.
- 探索可预测的感官运动体验的行为后果.
主要方法:
- 为小鼠开发了一个声学虚拟现实 (aVR) 系统.
- 训练小鼠将新的声音与运动运动联系起来.
- 分析了听觉和运动皮质活动和反应.
主要成果:
- aVR经历了对反射频率的选择性抑制听觉皮质反应.
- 听力皮层中抑制神经元的运动皮层激活得到加强.
- 小鼠在移动过程中可以更好地检测出非反应的音色.
结论:
- 经验塑造了一个动态的感官过器,
- 这种过器可以选择性地抑制运动的可预测声学后果.
- 适应性可塑性增强了移动过程中的听觉检测.
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