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儿童的支气管切除:诊断和治疗
Anne B Chang1, Andrew Bush2, Keith Grimwood3
1Child Health Division, Menzies School of Health Research, Casuarina, NT, Australia; Department of Respiratory Medicine, Children's Health Queensland, Brisbane, QLD, Australia; Queensland University of Technology, Brisbane, QLD, Australia.
Lancet (London, England)
|September 15, 2018
概括
早期诊断和治疗儿童支气管病,即使是轻微的病例,也可以阻止肺功能下降. 对非囊性纤维化儿科支气管病的治疗需要更多的研究.
科学领域:
- 儿童肺病学
- 呼吸系统医学
背景情况:
- 支气管扩张是一种不可逆转的支气管扩张,是全球慢性呼吸道疾病的重要原因,特别是在儿童中.
- 儿童支气管病的治疗策略往往缺乏高水平的证据,许多是从成人或囊性纤维化研究中推断出来的.
- 及时诊断和儿童早期干预对于儿童支气管病的管理至关重要.
研究的目的:
- 介绍目前的知识和儿童支气管切除症的最新定义.
- 审查儿童支气管病的管理中的争议,包括"可治疗的特征"概念.
- 突出了在诊断和管理非囊性纤维化支气管方面的儿科特异性数据的需要.
主要方法:
- 对现有文献和诊断方面的技术进步进行审查.
- 分析目前的管理策略,包括从其他条件中推断出来的策略.
- 讨论儿童支气管病的"可治疗特征"的概念.
主要成果:
- 轻微的支气管切除,即使最初看起来是不可逆转的,也可能在早期治疗后可以逆转,从而有可能阻止肺功能下降.
- 需要更多的非囊性纤维化儿科特异性数据来诊断和管理.
- "可治疗特征"的概念为儿童支气管病的治疗提供了一种新的方法.
结论:
- 即使在轻微的病例中,早期和最佳的治疗对于预防不可逆转的肺损伤至关重要.
- 为了有效诊断和治疗非囊性纤维化支气管,需要进一步的研究,以获得儿科特异性的证据.
- 采用"可治疗特征"的方法可以个性化并改善支气管切除症儿童的治疗结果.
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