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Updated: Jan 9, 2026

Generation of Defined Genomic Modifications Using CRISPR-CAS9 in Human Pluripotent Stem Cells
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Published on: September 25, 2019

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大规模并行精确基因组编辑揭示了功能性基因变异

Eilon Sharon1, Shi-An A Chen2, Neil M Khosla2

  • 1Department of Biology, Stanford University, Stanford, CA 94305, USA; Department of Genetics, Stanford University, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.

Cell
|September 25, 2018
PubMed
概括

研究人员使用CRISPR-Cas9基因组编辑来研究酵母中的16006种自然基因变异. 他们发现了数百种影响健康的变异, 大多是在促进区域, 揭示了对遗传结构和自然变异的洞察力.

关键词:
关于CRISPR的研究其他国家在 QTL一个进化适应性遗传变异基因组编辑酵母

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