蝙蝠海马形成中的非振荡相编码和同步
Tamir Eliav1, Maya Geva-Sagiv2, Michael M Yartsev1
1Department of Neurobiology, Weizmann Institute of Science, Rehovot 76100, Israel.
Cell
|October 16, 2018
概括
蝙蝠海马神经元显示时间编码的位置,类似于动物,但没有典型的theta振荡. 这一发现揭示了非振荡阶段编码,并突出了神经同步
科学领域:
- 神经科学
- 比较的认知
背景情况:
- 海马的振 (1-20 Hz) 传统上与记忆和空间时间编码有关.
- 之前对蝙蝠进行的研究报告说海马体缺乏节律, 质疑它的普遍作用.
研究的目的:
- 研究蝙蝠海马的时间编码机制是否与动物不同.
- 为了确定空间编码是否在哺乳动物物种中普遍存在,尽管振荡活动的变化.
主要方法:
- 蝙蝠海马神经元中的电生理记录.
- 分析神经元发射模式和场潜在的波动.
- 研究与蝙蝠移动有关的相位编码和相位前行.
主要成果:
- 蝙蝠海马神经元表现出强大的时间编码位置,
- 神经元与非节律场的潜在波动强烈同步, 尽管缺席的泰达振荡.
- 在一些蝙蝠海马神经元中观察到相位前行和相位编码.
结论:
- 哺乳动物的大脑可以利用非振荡相代码来获取时间和空间信息.
- 神经同步在海马功能中起着至关重要的作用,
- 时间编码是各种哺乳动物的保存功能,包括蝙蝠.
相关概念视频
Three-Phase Short Circuit—Unloaded Synchronous Machine
696
Conducting a three-phase short circuit test on an unloaded synchronous machine helps understand its impact on the system. The AC fault current's oscillogram, with the DC offset removed, reveals that the waveform amplitude decreases from an initially high value to a steady-state level for one phase of the machine.
This behavior occurs due to the magnetic flux produced by the short-circuit armature currents. Initially, these currents follow high-reluctance paths but eventually shift to...
This behavior occurs due to the magnetic flux produced by the short-circuit armature currents. Initially, these currents follow high-reluctance paths but eventually shift to...
696
lncRNA - Long Non-coding RNAs
9.9K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
9.9K
lncRNA - Long Non-coding RNAs
3.7K
3.7K
Phase II Reactions: Glutathione Conjugation and Mercapturic Acid Formation
932
Glutathione, a tripeptide made up of glutamate, cysteine, and glycine, is a critical player in the detoxification of drugs and xenobiotics via a process known as glutathione conjugation or mercapturic acid formation. This phase II biotransformation reaction involves the covalent binding of glutathione to a drug or its metabolite, enhancing the compound's water solubility and enabling its excretion.
Several distinctive characteristics distinguish glutathione conjugation from other phase II...
Several distinctive characteristics distinguish glutathione conjugation from other phase II...
932
Nursing Code of Ethics
4.5K
The Nursing Code of Ethics sets the ethical benchmark for the profession, and guides nurses in ethical analysis and decision making at the societal, organizational, and clinical levels. The code encompasses showing compassion and respect for the patient, their families, and communities in all circumstances while committing to providing patient-centered care. In addition, the code states that nurses must advocate for the patient by defending a cause or recommendation to protect their rights,...
4.5K
Phase Diagrams
50.2K
A phase diagram combines plots of pressure versus temperature for the liquid-gas, solid-liquid, and solid-gas phase-transition equilibria of a substance. These diagrams indicate the physical states that exist under specific conditions of pressure and temperature and also provide the pressure dependence of the phase-transition temperatures (melting points, sublimation points, boiling points). Regions or areas labeled solid, liquid, and gas represent single phases, while lines or curves represent...
50.2K


