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相关概念视频

Generator Voltage Control01:21

Generator Voltage Control

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Generator voltage control is crucial for maintaining the stable operation of synchronous generators and wind turbines. In older models, a DC generator driven by the rotor delivers DC power to the rotor's field winding, and the power is transferred through slip rings and brushes. In the latest models, static or brushless exciters are used. Static exciters rectify AC power from the generator terminals and then transfer the DC power directly to the rotor. Brushless exciters, on the other hand, use...
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3D Modeling of Dendritic Spines with Synaptic Plasticity
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时钟生成的时间代码确定突触可塑性以控制睡眠

Masashi Tabuchi1, Joseph D Monaco2, Grace Duan1

  • 1Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.

Cell
|October 16, 2018
PubMed
概括
此摘要是机器生成的。

在Drosophila时钟神经元中,时间尖峰模式控制着兴奋和睡眠,独立于发射速度. 这项研究确定了分子通路并证明了时间编码

关键词:
类植物生物时钟睡觉时间突触可塑性时间编码

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相关实验视频

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科学领域:

  • 神经科学
  • 时间生物学
  • 分子生物学

背景情况:

  • 神经元使用速率编码 (发射频率) 和时间编码 (发射时间/模式) 来编码信息.
  • 对于行为控制的时代代码及其潜在的分子机制的充分性是有争议的.

研究的目的:

  • 调查不同时间尖峰模式,与发射率分开,编码时间依赖的唤醒和调节Drosophila的睡眠.
  • 确定负责生成昼夜依赖时间尖峰模式的分子途径.

主要方法:

  • 使用Drosophila时钟神经元来研究神经编码.
  • 进行大规模的基因查以确定分子途径.
  • 研究了尖峰形态和离子流变化.

主要成果:

  • 不同的时间尖峰模式, 独立于发射速度, 已被证明编码时间依赖的唤醒和调节睡眠.
  • 识别了调节尖峰时间的日间依赖离子流和尖峰形态变化的分子途径.
  • 已经证明, 仅仅是白天的激增模式, 就能诱导下游激发神经元的塑性.

结论:

  • 时间编码在行为中起着因果作用,特别是在调节兴奋和睡眠方面.
  • 定义了一种新型的突触可塑性,
  • 阐明了行为相关时间代码生成的分子机制.