一个中皮层多巴胺循环使声乐行为具有文化传递
Masashi Tanaka1,2, Fangmiao Sun3,4, Yulong Li3,4,5
1Department of Neurobiology, Duke University, Durham, NC, USA.
Nature
|October 19, 2018
概括
幼通过识别和复制导师来学习歌曲, 不仅仅是通过听歌. 一个涉及多巴胺的特定大脑循环帮助幼鸟编码和模仿导师歌曲以传递文化.
科学领域:
- 神经科学
- 动物的行为
- 生物声学
背景情况:
- 文化传播的行为依赖于学生和导师的互动.
- 大脑中辅导员识别和行为编码的机制尚不清楚.
- 斑马幼儿的歌曲学习是社会依赖的,需要与导师互动.
研究的目的:
- 调查幼斑马的辅导识别和歌曲模仿的神经机制.
- 确定大脑区域和神经化学途径参与社会学习的发音.
- 为了阐明歌唱教师的社交线索如何促进歌曲复制.
主要方法:
- 在中脑周水管灰色 (PAG) 和HVC中进行电生理记录.
- 使用药物阻断剂对HVC进行多巴胺信号操纵.
- 在HVC中对PAG终端进行光遗传刺激.
- 在HVC中分析歌曲结构和辅导歌曲反应的出现.
主要成果:
- 幼的PAG中的神经元由歌唱导师选择激活.
- 在HVC中释放的多巴胺由歌唱导师触发, 对于编码导师歌曲至关重要.
- 阻断HVC中的多巴胺信号阻止了歌曲的复制.
- 在HVC中刺激PAG终端与歌曲复制驱动器配对.
- 接触歌唱导师很快就会引发HVC反应并增加学生的歌曲复杂性.
结论:
- 一个中脑的多巴胺循环检测辅导员并编码他们的歌曲来进行声学.
- 通过将社会线索与歌曲的表现联系起来,
- 社交互动和多巴胺信号传递对于精确模仿语音学习至关重要.
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