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Updated: Feb 3, 2026

High-throughput Nitrobenzoxadiazole-labeled Cholesterol Efflux Assay
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通过胆固醇在酵母和动态核极化NMR中的标记来确定胆固醇与膜蛋白的结合

Matthew R Elkins1, Ivan V Sergeyev2, Mei Hong1

  • 1Department of Chemistry , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.

Journal of the American Chemical Society
|October 20, 2018
PubMed
概括

这项研究引入了一种新的NMR光谱法,用于确定膜蛋白上的胆固醇结合点. 该技术成功地绘制了胆固醇与流感M2蛋白的相互作用,揭示了病毒芽的关键细节.

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