在澳大利亚的初级保健中机会性克拉米迪亚检测的有效性:一个集群随机对照试验
Jane S Hocking1, Meredith Temple-Smith2, Rebecca Guy3
1Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia.
Lancet (London, England)
|October 23, 2018
概括
在澳大利亚的初级保健中,机会性克拉米迪亚检测没有显著降低年轻成年人的克拉米迪亚患病率. 这项研究表明,广泛的查可能不是针对该感染的有效人口水平策略.
科学领域:
- 公共卫生
- 传染性疾病
- 主要护理医学
背景情况:
- 在高收入国家推广生殖器甲状腺炎查.
- 它在人口层面的有效性仍有争议.
- 这项研究调查了澳大利亚初级保健中的机会性测试.
研究的目的:
- 评估基于临床的多面性克拉米迪亚检测干预措施对年轻成年人 (16-29岁) 克拉米迪亚患病率的影响.
- 评估机会性查在初级保健机构的有效性.
主要方法:
- 参与澳大利亚农村城镇的集群随机对照试验.
- 干预包括提醒,教育,支付和测试率的反.
- 通过干预前后的调查估计了克拉米迪亚的患病率.
主要成果:
- 在干预组 (5. 0% 至 3. 4%) 和对照组 (4. 6% 至 3. 4%) 中,克拉米迪亚的患病率均下降.
- 两组之间降低患病率的差异没有统计学意义 (OR 0. 9, 95% CI 0. 5至 1. 5).
- 超过18万名年轻人参与了120家诊所的研究.
结论:
- 在初级保健中进行机会性克拉米迪亚检测可能无法在人口水平上显著降低患病率.
- 这些发现表明当前查策略的局限性.
- 对持续吸收和有效性的进一步研究是有必要的.
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