形态无活化的核糖酶的光化学救援

Brandon L Greene1, JoAnne Stubbe, Daniel G Nocera1

  • 1Department of Chemistry and Chemical Biology , Harvard University , Cambridge , Massachusetts 02138 , United States.

概括

一级核酸减少酶 (RNR) 的活性依赖于子单元之间的基因转移 (RT). 一个特定的突变 (E350X) 阻止了这一点,但光化学救援揭示了E350

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