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扩大核酸重编码工具包:揭示RNA群体动态与6-瓜素

Lea Kiefer1,2, Jeremy A Schofield1,2, Matthew D Simon1,2

  • 1Department of Molecular Biophysics & Biochemistry , Yale University , New Haven , Connecticut 06511 , United States.

Journal of the American Chemical Society
|October 25, 2018
PubMed
概括

研究人员为TimeLapse测序引入了6-thioguanosine (s6G) 重编码,使得对RNA动态的新见解成为可能. 这种方法将核酸重编码扩展到4 - 氨酸 (s4U) 以分析新合成的RNA.

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