相关实验视频
Updated: Feb 3, 2026

09:58
Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
12.3K
由DNA纳米机控制的光驱动的ATP跨膜传输
Pei Li1,2, Ganhua Xie1, Pei Liu1,3
1CAS Key Laboratory of Bio-Inspired Materials and Interfacial Science , Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190 , People's Republic of China.
Journal of the American Chemical Society
|October 30, 2018
概括
科学家们创造了光控制的DNA纳米机器,用于在膜上选择性地运输ATP. 这种仿生系统为分子分离和跨膜传输提供了新的可能性.
科学领域:
- 仿生工程
- 纳米技术
- 分子运输
背景情况:
- 生物机器维持生物体的新陈代谢.
- 人工分子发动机的灵感来自大自然.
- 通过膜进行选择性生物分子传输是具有挑战性的.
研究的目的:
- 使用光控制的DNA纳米机来建立ATP传输系统.
- 通过人工纳米通道进行选择性货物运输.
主要方法:
- 将光控制的DNA纳米机组成人工纳米通道.
- 使用交替光辐射来控制运输.
- 运输腺三酸盐 (ATP) 分子
主要成果:
- 成功建立了一个ATP运输系统.
- 通过光控制的DNA纳米机器,通过聚合物膜进行选择性货物运输.
- 展示了通过交替光照照射来引导货物的能力.
结论:
- 光控制的DNA纳米机器可以实现选择性跨膜传输.
- 这种技术为大规模运输和分离提供了新的方法.
- 潜在的应用包括光驱的其他分子和离子的运输.
相关概念视频
ATP Driven Pumps I: An Overview
9.9K
ATP-driven pumps, also known as transport ATPases, are integral membrane proteins. They have binding sites for ATP located on the membrane's cytosolic side and the ion-conducting domain in the transmembrane region. These pumps use the free energy released from ATP hydrolysis to move the solutes across cell membranes against an electrochemical gradient.
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
There are four main types of ATP-driven pumps - P-type, V-type, F-type, and ABC transporter. All these pumps are of varying complexities and...
9.9K
ATP Driven Pumps II: P-type Pumps
6.4K
The P-type pumps are a large family of integral membrane transporter ATPases. They are divided into five major types based on substrate specificity, from I to V.
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
A typical P-type pump has three cytosolic domains: nucleotide-binding (N), phosphorylation (P), and activator (A) domains. These domains are connected to the membrane-spanning helices by short amino acid segments. ATP hydrolysis and covalent phosphoenzyme intermediate formation are crucial parts of the catalytic cycle. At the highly...
6.4K
ATP Driven Pumps III: V-type Pumps
4.8K
V-type pumps are ATP-driven pumps found in the vacuolar membranes of plants, yeast, endosomal and lysosomal membranes of animal cells, plasma membranes of a few specialized eukaryotic cells, and some prokaryotes. They are also known as the V1Vo-ATPase, that couple ATP hydrolysis to transport protons against a concentration gradient.
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
The peripheral or cytosolic V1 domain with eight subunits is involved in ATP hydrolysis. The integral or transmembrane V0 domain containing at least five subunits...
4.8K
ATP Yield
78.9K
Cellular respiration produces 30 - 32 ATP per glucose molecule. Although most of the ATP results from oxidative phosphorylation and the electron transport chain (ETC), 4 ATP are gained beforehand (2 from glycolysis and 2 from the citric acid cycle).
The ETC is embedded in the inner mitochondrial membrane and is comprised of four main protein complexes and an ATP synthase. NADH and FADH2 pass electrons to these complexes, which pump protons into the intermembrane space. This distribution of...
The ETC is embedded in the inner mitochondrial membrane and is comprised of four main protein complexes and an ATP synthase. NADH and FADH2 pass electrons to these complexes, which pump protons into the intermembrane space. This distribution of...
78.9K
Xylem and Transpiration-driven Transport of Resources
26.7K
The xylem of vascular plants distributes water and dissolved minerals that are taken up by the roots to the rest of the plant. The cells that transport xylem sap are dead upon maturity, and the movement of xylem sap is a passive process.
26.7K
Short-distance Transport of Resources
17.7K
Short-distance transport refers to transport that occurs over a distance of just 2-3 cells, crossing the plasma membrane in the process. Small uncharged molecules, such as oxygen, carbon dioxide, and water, can diffuse across the plasma membrane on their own. In contrast, ions and larger molecules require the assistance of transport proteins due to their charge or size. Transport across membranes also occurs within individual cells, playing a variety of essential roles for the plant as a whole.
17.7K

