针对性神经技术可以恢复脊髓损伤患者的行走
Fabien B Wagner1,2, Jean-Baptiste Mignardot1,2, Camille G Le Goff-Mignardot1,2
1Center for Neuroprosthetics and Brain Mind Institute, School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.
Nature
|November 2, 2018
概括
有针对性的脊髓刺激神经技术使慢性患者能够自发行走. 这种时空刺激恢复了肌肉控制,从而改善了运动功能和脊髓损伤后的恢复.
科学领域:
- 神经科学
- 生物医学工程
- 康复医学
背景情况:
- 脊髓损伤经常导致严重的运动缺陷和.
- 尽管进行了广泛的康复治疗,但许多人仍然存在永久的运动缺陷.
研究的目的:
- 引入针对性脊髓刺激的神经技术,以恢复慢性脊髓损伤患者的自发行走.
- 研究时空刺激对恢复运动控制的有效性.
主要方法:
- 使用一个植入的脉冲发生器实时触发能力.
- 提供空间选择性,时空刺激到腰部神经脊髓,与预期的运动定时.
- 在刺激治疗的同时实施了康复计划.
主要成果:
- 在一周内,时空刺激恢复了地面行走过程中的肌肉的适应性控制.
- 在康复期内,运动能力有所改善.
- 参与者在没有刺激的情况下恢复了自愿肌肉控制,并在几个月后可以在生态环境中进行步行/骑自行车.
结论:
- 脊髓刺激神经技术为SCI后的神经恢复提供了框架.
- 这种方法支持患者的日常生活活动.
- 这项研究表明,在受伤后恢复自发运动控制的潜力.
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