Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Resistivity01:22

Resistivity

4.6K
When a voltage is applied to a conductor, an electrical field is generated, and charges in the conductor feel the force due to the electrical field. The current density that results depends on the electrical field and the properties of the material. In some materials, including metals at a given temperature, the current density is approximately proportional to the electrical field. In these cases, the current density can be modeled as:
4.6K
Resistance01:19

Resistance

6.0K
When a current moves through any conductor, the conductor causes some level of difficulty for the current to flow. The measure of that difficulty is known as the resistance of the material and is represented by R. Every material has its own resistance. In the case of conductors, heat is emitted whenever a current passes through them. Resistance depends on the resistivity of the material. Resistivity is a characteristic of the material used to fabricate electrical components, whereas the...
6.0K
Gene Flow02:39

Gene Flow

37.8K
Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
37.8K
Equivalent Resistance01:16

Equivalent Resistance

982
In circuit analysis, situations often arise where resistors are neither in series nor parallel configurations. To tackle such scenarios, three-terminal equivalent networks like the wye (Y) (Figure 1 (a)) or tee (T) and delta (Δ) (Figure 1 (b)) or pi (π) networks come into play. These networks offer versatile solutions and are frequently encountered in various applications, including three-phase electrical systems, electrical filters, and matching networks.
982
Resistance and Conductance01:25

Resistance and Conductance

515
A conductor's DC resistance at a given temperature is influenced by its resistivity, length, and cross-sectional area. Resistivity is an inherent property of the conductor material, with annealed copper serving as the international standard for measurement. For instance, the resistivity of hard-drawn aluminum at 20 degrees Celsius is 61% of the standard conductivity of annealed copper.
Various factors impact the resistance of a conductor. Spiraling in stranded conductors increases their...
515
Rolling Resistance01:21

Rolling Resistance

663
When a solid cylinder rolls steadily on a rigid surface, the normal force applied by the surface on the cylinder is perpendicular to the tangent at the contact point. However, since no materials are entirely rigid, the surface's reaction to the cylinder involves a range of normal pressures.
For instance, imagine a hard cylinder rolling on a comparatively soft surface. The cylinder's weight compresses the surface beneath it. As the cylinder moves, the material in front of it slows down due to...
663

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Capillary bundling of microtubules by condensates.

bioRxiv : the preprint server for biology·2026
Same author

Room-Temperature Aerosol Dehydration of Green Fluorescent Protein.

Drying technology·2026
Same author

Ultrasensitive Detection of Macromolecules in Water Via Flowing Nanoparticles on a Microchip.

Nano letters·2026
Same author

Voltage dynamics of cortical dendrites in vivo.

Nature neuroscience·2026
Same author

Soft-Lubrication Drainage and Rupture in Particle-Driven Vesicles.

Physical review letters·2026
Same author

Correction to "Optical Single-Channel Recording via Diffusional Confinement in Membrane Tethers".

ACS nano·2026
Same journal

A viral ORFeome library for systems-level genetic dissection of host-pathogen interactions.

Cell·2026
Same journal

Co-option of lysosomal machinery shapes the evolution of the intracellular photosymbiosis supporting coral reefs.

Cell·2026
Same journal

LEF1 and niche factors determine T cell stemness across chronic diseases.

Cell·2026
Same journal

Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders.

Cell·2026
Same journal

Four-dimensional molecular mapping from a spatial snapshot reveals the dynamics of hair follicle organogenesis.

Cell·2026
Same journal

Whole-cell particle-based digital twin simulations from 4D lattice light-sheet microscopy data.

Cell·2026
查看所有相关文章

相关实验视频

Updated: Feb 3, 2026

Quantitative Measurement of GLUT4 Translocation to the Plasma Membrane by Flow Cytometry
05:39

Quantitative Measurement of GLUT4 Translocation to the Plasma Membrane by Flow Cytometry

Published on: November 7, 2010

27.1K

细胞膜抵抗流动

Zheng Shi1, Zachary T Graber2, Tobias Baumgart2

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA; Howard Hughes Medical Institute.

Cell
|November 6, 2018
PubMed
概括
此摘要是机器生成的。

与流体马赛克模型相反,膜张力变化在完整的细胞中不会传播很远. 局部膜张力,而不是远程传播,影响细胞过程,如离子通道活动和囊泡融合.

关键词:
细胞机械膜信号膜张力有孔的介质病理学

更多相关视频

Measurement of Mitochondrial Mass and Membrane Potential in Hematopoietic Stem Cells and T-cells by Flow Cytometry
07:57

Measurement of Mitochondrial Mass and Membrane Potential in Hematopoietic Stem Cells and T-cells by Flow Cytometry

Published on: December 26, 2019

13.0K
Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein
10:43

Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein

Published on: December 3, 2010

22.9K

相关实验视频

Last Updated: Feb 3, 2026

Quantitative Measurement of GLUT4 Translocation to the Plasma Membrane by Flow Cytometry
05:39

Quantitative Measurement of GLUT4 Translocation to the Plasma Membrane by Flow Cytometry

Published on: November 7, 2010

27.1K
Measurement of Mitochondrial Mass and Membrane Potential in Hematopoietic Stem Cells and T-cells by Flow Cytometry
07:57

Measurement of Mitochondrial Mass and Membrane Potential in Hematopoietic Stem Cells and T-cells by Flow Cytometry

Published on: December 26, 2019

13.0K
Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein
10:43

Expression, Detergent Solubilization, and Purification of a Membrane Transporter, the MexB Multidrug Resistance Protein

Published on: December 3, 2010

22.9K

科学领域:

  • 细胞生物学
  • 生物物理

背景情况:

  • 流体马赛克模型将等离子体膜描述为流体,允许流动以应对张力梯度.
  • 人们普遍认为,膜张力迅速传播,介导长距离细胞内信号传递.

研究的目的:

  • 研究完整细胞与细胞斑块中的膜张力的传播动态.
  • 确定膜张力是否可以作为远程信号机制.

主要方法:

  • 在细胞附着血栓和完整细胞中进行膜张力传播的实验观察.
  • 结合细胞骨结合的跨膜蛋白抗性的流体动态模型的开发.
  • 在HeLa细胞中测量张力传播扩散系数.
  • 在初级内皮细胞中分析机械敏感离子通道激活和囊泡融合.

主要成果:

  • 膜张力传播在细胞斑中是快速的,但在完整的细胞中被显著抑制.
  • 一个流体动态模型解释了由于细胞骨架结合的跨膜蛋白的抑制传播.
  • 张力在HeLa细胞中扩散,扩散系数约为0.024μm2/s.
  • 内皮细胞的局部膜张力增加导致局部离子通道激活和囊泡融合.

结论:

  • 膜张力不能作为长距离细胞内信号传递的媒介.
  • 膜张力的局部变化对不同的亚细胞域过程负责.