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微生物产生的伊米达酸会通过mTORC1损害胰岛素信号

Ara Koh1, Antonio Molinaro1, Marcus Ståhlman1

  • 1Department of Molecular and Clinical Medicine/Wallenberg Laboratory, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

Cell
|November 8, 2018
PubMed
概括

一种肠道微生物的代谢物,伊米达,在2型糖尿病中升高,通过破坏胰岛素信号通路而降低葡萄糖耐受性. 这一发现表明伊米达在代谢疾病的发展中可能起作用.

关键词:
美国国税局西提丁 (histidin)艾米达酸盐在 mTORC1微生物组其他类型没有.

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