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Updated: Feb 2, 2026

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在ATP结合和基质结合状态中被困的人类ABCG2突变的冷EM结构

Ioannis Manolaridis1, Scott M Jackson1, Nicholas M I Taylor2,3

  • 1Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zurich, Switzerland.

Nature
|November 9, 2018
PubMed
概括

这项研究揭示了ABCG2传送器功能的结构机制. 高分辨率的冷EM结构显示了ATP结合如何驱动细胞膜的基质转移.

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