脊椎动物半圆通道的进化
Shinnosuke Higuchi1,2, Fumiaki Sugahara3,4, Juan Pascual-Anaya4
1Department of Biology, Graduate School of Science, Kobe University, Kobe, Japan.
Nature
|December 7, 2018
概括
脊椎动物内耳的演变是明确的:鱼单半圆通道是一种衍生性特征,而脊椎动物的侧面通道则是次要演变的.
科学领域:
- 进化生物学
- 发育生物学
- 比较解剖学
背景情况:
- 脊椎动物的内耳有三个半圆通道,对于进化研究至关重要.
- 没有的脊椎动物有两个通道,缺少侧面通道.
- 现代的旋流体 (鱼和鱼) 呈现出不同的运河数量,鱼有一个,鱼通常有两个,这使进化解释复杂化.
研究的目的:
- 调查旋转的内耳的发育轨迹,特别是鱼和鱼.
- 澄清脊椎动物中半圆通道数和侧通道的进化起源.
主要方法:
- 详细观察鱼 (Lethenteron camtschaticum) 和鱼 (Eptatretus burgeri) 的眼囊分化情况.
- 在循环体内内耳部发育过程中分析基因表达模式,包括OTX基因.
主要成果:
- 兰普里内耳的发育开始于两个低谷,类似于早期的耳发育.
- 这些陷合并形成一个单一的运河,
- 鱼单通道是一种二次衍生的特征,而不是原始的.
- 体的侧面通道是通过下游的发育途径进化而来的,而不是新的基因表达.
结论:
- 鱼的单半圆通道是一种衍生性特征, 挑战了以前的原始性假设.
- 脊椎动物内耳的进化路径,特别是侧面通道的获得,通过发育洞察得到了阐明.
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