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无症状动脉样硬化疾病的可视化为最佳心血管预防 (VIPVIZA):一个实用性的,开放的,随机对照试验
Ulf Näslund1, Nawi Ng2, Anna Lundgren2
1Heart Centre and Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Lancet (London, England)
|December 8, 2018
概括
通过降低Framingham风险评分,对亚临床动脉样硬化的图像超声波信息改善了心血管疾病的预防. 这种视觉辅助工具可以提高人们对生活方式和药物治疗的坚持,从而解决一次性预防的关键问题.
科学领域:
- 心脏病学
- 预防医学
- 医学成像
背景情况:
- 心血管疾病的初级预防受阻于对指导方针的不严格遵守.
- 亚临床动脉样硬化,特别是动脉动脉样硬化,是主要预防的目标.
- 需要新的策略来改善患者和医生的心血管疾病预防参与.
研究的目的:
- 评估基于超声波的关于临床下动脉样硬化的图像信息是否能改善心血管疾病的预防.
- 评估这项干预措施对医疗保健提供者和个人的影响.
- 确定对已确定的心脏病风险评分的影响.
主要方法:
- 一个实用的,开放的,随机对照试验 (VIPVIZA) 整合到基于人口的预防计划中.
- 参与者 (年龄在40岁,50岁,60岁,有风险因素) 接受了标准护理或图像性动脉超声波结果以及护士咨询.
- 主要结局包括1年后的弗雷明汉风险评分 (FRS) 和欧洲系统冠状动脉风险评估 (SCORE) 的变化.
主要成果:
- 在1年后,研究小组之间观察到FRS和SCORE的显著差异.
- 干预组的FRS下降,而对照组的FRS增加.
- 在干预组中,Score在两组中都增加,但在干预组中显著减少.
结论:
- 亚临床动脉样硬化的图像表示有助于预防心血管疾病.
- 这种视觉反方法显示了改善药物和生活方式改变的潜力.
- 进一步开发这些方法是有必要的,以对抗心脏病预防的低依从性.
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