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原生透镜连接素46/50细胞间通道的结构

Janette B Myers1, Bassam G Haddad1, Susan E O'Neill1

  • 1Department of Chemistry, Portland State University, Portland, OR, USA.

Nature
|December 14, 2018
PubMed
概括

研究人员使用冷EM研究了透镜间隙连接通道 (Cx46/50),揭示了遗传性白内障的结构洞察力. 这项研究阐明了连接素协同组装如何影响道功能和疾病机制.

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