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Updated: Feb 1, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
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在自闭症,精神分裂症和双相情感障碍中转录组范围的异型水平调节失调

Michael J Gandal, Pan Zhang, Evi Hadjimichael

    Science (New York, N.Y.)
    |December 15, 2018
    PubMed
    概括

    自闭症谱系障碍 (ASD),精神分裂症和双相情感障碍等精神疾病的遗传风险显著影响基因表达和拼接. 这项研究揭示了广泛的转录基因变化,并确定了新的神经免疫机制.

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