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男人对婴儿的多感官攻击逻辑
Yoh Isogai1, Zheng Wu2, Michael I Love3
1Howard Hughes Medical Institute, Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA; Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London W1T 4JG, UK.
Cell
|December 15, 2018
概括
由于特定的物理和化学线索, 处女雄性小鼠攻击幼, 涉及到鼻受体. 这种攻击反应不是幼特有的,突出显示雄性小鼠的复杂感官处理.
科学领域:
- 神经科学
- 动物的行为
- 化学生态学
背景情况:
- 新生儿需要成年人的照顾,
- 雄性对幼的攻击需要鼻器官的功能.
- 特定的婴儿触发男性侵略的线索仍未确定.
研究的目的:
- 为了确定婴儿的特征, 引起处女雄性小鼠的攻击性反应.
- 为了阐明鼻受体和激素化合物参与了这种攻击行为.
主要方法:
- 使用重建的幼犬线索开发了一种行为范式.
- 通过婴儿线索激活的已识别的鼻受体.
- 使用遗传删除来确认受体参与攻击.
- 使用生物化学分化来分离费洛蒙化合物.
主要成果:
- 婴儿形态特征和唾液化学信号强烈地引起男性的攻击性.
- 鉴定了七个口鼻受体,其中Vmn2r65和Vmn2r88特别涉及侵略性.
- 分离了两种费洛蒙化合物,即下腺蛋白C和血红蛋白.
- 发现的线索和受体并不仅限于幼.
结论:
- 在处女男性中, 婴儿间接的攻击性涉及识别身体特征和化学线索.
- 这种攻击的感官机制并不特定于幼犬.
- 这项研究揭示了雄性老鼠的复杂化学传感处理.
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