在久坐的中年成年人中进行了两年的高强度运动训练后,左心房的电机改造
David A McNamara1,2, Norman Aiad1,2, Erin Howden2
1Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas (D.A.M., N.A., M.S.L., S.S., B.D.L.).
Circulation
|December 28, 2018
概括
在久坐不动的成年人中,高强度运动在24个月内导致左心房显著扩大. 这种机械重塑发生在没有电气变化的情况下,
科学领域:
- 心脏病学
- 运动生理学
- 心脏重塑
背景情况:
- 适度运动可以降低心房的风险.
- 运动员的强度训练与AF发生率的增加有关.
- 长期高强度运动对非运动员心脏重塑的影响尚不清楚.
研究的目的:
- 研究24个月高强度运动对左心室 (LA) 机械和电力改造的影响.
- 评估中年,久坐不动的成年人进行结构化的运动计划的变化.
主要方法:
- 随机对照试验对61名久坐不动的成年人进行 (53±5年).
- 干预:高强度运动10个月,然后维持14个月,与伸展/平衡控制相比.
- 评估包括LA/LV体积的3D回声心脏学和电气参数的心电学.
主要成果:
- 在10个月后,高强度运动导致LA和LV体积的比例增加.
- 在24个月内,LA量继续显著增加 (比基线增加了55%),超过LV变化.
- 两组之间没有观察到心房电特性或AF检测的显著变化.
结论:
- 二十四个月的高强度运动会引起左心房的显著机械改造,
- 对于机械与电气适应运动可能存在不同的门.
- 这些发现提供了与高强度运动与心房动风险相关的潜在机制.
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