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Updated: Jan 31, 2026

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
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慢性卡尔莫杜林-基因酶II激活驱动突变特异性多变性心肌病变的疾病进展

Sarah J Lehman1, Lauren Tal-Grinspan2, Melissa L Lynn3

  • 1Department of Physiological Sciences (S.J.L.), University of Arizona, Tucson.

Circulation
|December 28, 2018
PubMed
概括

向激活卡尔莫杜林酶II (CaMKII) 显示出对缩性心肌病 (HCM) 治疗的前景. 然而,治疗效应是突变特异性的,需要对个性化干预进行分子层面的理解.

关键词:
通道阻塞剂 通道阻塞剂信号传递的.- 卡尔莫杜林依赖的蛋白质激酶.心肌病,高性,家族性心肌病.

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