相关实验视频

Updated: Jan 31, 2026

Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors
09:57

Imaging Membrane Potential with Two Types of Genetically Encoded Fluorescent Voltage Sensors

Published on: February 4, 2016

11.3K

用基因可定位的电压指示器监视神经膜潜力

Vincent Grenier, Brittany R Daws, Pei Liu

    Journal of the American Chemical Society
    |January 11, 2019
    PubMed
    概括

    新的VoltageSpy染料可以精确地测量基因定义的神经元中的电压变化. 这些化学合成的光探针可以针对特定的细胞,为神经元活动成像提供高灵敏度和快速响应时间.

    更多相关视频

    Biosensing Motor Neuron Membrane Potential in Live Zebrafish Embryos10:18

    Biosensing Motor Neuron Membrane Potential in Live Zebrafish Embryos

    Published on: June 26, 2017

    7.1K
    Imaging Mitochondrial Ca2+ Uptake in Astrocytes and Neurons using Genetically Encoded Ca2+ Indicators GECIs07:46

    Imaging Mitochondrial Ca2+ Uptake in Astrocytes and Neurons using Genetically Encoded Ca2+ Indicators GECIs

    Published on: January 22, 2022

    4.6K

    相关概念视频

    The Resting Membrane Potential01:21

    The Resting Membrane Potential

    Overview
    142.4K
    Indicators02:39

    Indicators

    Certain organic substances change color in dilute solution when the hydronium ion concentration reaches a particular value. For example, phenolphthalein is a colorless substance in any aqueous solution with a hydronium ion concentration greater than 5.0 × 10−9 M (pH < 8.3). In more basic solutions where the hydronium ion concentration is less than 5.0 × 10−9 M (pH > 8.3), it is red or pink. Substances such as phenolphthalein, which can be used to determine the pH of a solution, are...
    60.6K
    Resting Membrane Potential01:24

    Resting Membrane Potential

    The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane.
    The Inside of a Neuron is More Negative
    The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
    21.7K
    Voltage01:13

    Voltage

    The movement of electrons in a conductor requires some form of energy or work, usually provided by an external force, like a battery. This force is called the electromotive force or voltage. The voltage between two points, referred to as points "a" and "b," in an electric circuit is the energy (or work) needed to move a unit charge from point "a" to point "b," and this relationship is expressed mathematically as
    4.2K
    Multiple Voltage Sources01:25

    Multiple Voltage Sources

    Generally, a single battery is not enough to power some devices. In such cases, batteries can be combined in two ways: in series or in parallel.
    In series, the positive terminal of one battery is connected to the negative terminal of another battery. Hence, the voltage of each battery is added to give the net voltage, which is increased because each battery boosts the electrons that enter it. The same current flows through each battery because they are connected in series.
    Batteries are...
    1.8K
    Voltage Dividers01:14

    Voltage Dividers

    In electrical circuits, resistors can be connected in series, sequentially linked one after the other. In a series configuration, the same current flows through each resistor. Ohm's law is a fundamental principle to understand the behavior of resistors in series. It expresses the voltage across these resistors in terms of the current and resistance.
    Kirchhoff's voltage law implies that the sum of the voltages across the resistors in series equals the source voltage. This means that the current...
    1.3K