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CRIF1-CDK2接口抑制剂:一种前所未有的细胞辐射敏感性调节策略

Qian Ran1, Yang Xiang1, Preyesh Stephen2

  • 1Department of Blood Transfusion, Irradiation Biology Laboratory , Xinqiao Hospital , Chongqing , 400037 , China.

Journal of the American Chemical Society
|January 18, 2019
PubMed
概括

针对CRIF1- CDK2相互作用的新药候选药物可以选择性地抑制骨髓瘤细胞的增殖并增强放射敏感性. 这种方法克服了克林依赖激酶 (CDK) 针对癌症治疗的选择性问题.

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