通过结构控制增强手术活动:两个内在手术黄金纳米集群的手术合成和可逆互转
Jia-Qi Wang1, Zong-Jie Guan2, Wen-Di Liu1
1Department of Chemistry , Tsinghua University , Beijing 10084 , PR China.
Journal of the American Chemical Society
|January 19, 2019
概括
研究人员使用BINAP合成了新的性金纳米集群. 结构修改增强了手术活动, 为金纳米集群实现了创纪录的异构系数.
科学领域:
- * 无机化学
- * 纳米技术
- * 材料科学
背景情况:
- * 黄金纳米集群因其独特的光学特性而引起关注.
- 精确控制它们的结构和性对于调整它们的表现至关重要.
- 在金纳米集群的合成和特性中,连接物选择起着关键作用.
研究的目的:
- * 合成和描述新的内在性黄金纳米集群.
- * 调查不同黄金纳米集群物种之间的结构互换.
- * 探索结构修改对手术特性的影响,特别是循环二重体 (CD) 信号.
主要方法:
- 使用BINAP作为奇拉连接体进行原子精确金纳米集团的单合成.
- 使用X射线晶体学对Au9和Au10纳米团进行隔离和结构确定.
- * 图形特征的表征,包括圆形二光学 (CD) 光谱.
- 通过添加或删除特定的配体来研究可逆结构互转.
主要成果:
- *成功合成了两种新型性黄金纳米集群:[Au9(R-/S-BINAP) 4(CF3COO) 3和[Au10(R-/S-BINAP) 4(p-CF3C6H4CC) 3COO.
- * 已确定的晶体结构显示了Au9的C2对称性和Au10的C1对称性.
- * 证明了Au9和Au10纳米团之间的可逆互转.
- * 在从Au9转换到Au10时观察到CD信号的显著增强.
- * 在可见区域的Au10纳米团中达到最高的异构系数 (高达6.6×10−3),大约是Au9纳米团的两倍.
结论:
- 合成了具有独特结构和高产量的新奇金纳米集群.
- * Au9和 Au10纳米集群之间的结构互换是可以实现的,并且影响了手术性质.
- 通过配体引入调节金纳米集群的结构提供了调整其光学活动的途径.
- 这些发现为设计用于先进应用的金纳米集群提供了基础.
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