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Updated: Jan 30, 2026

Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases
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Crystallizing Membrane Proteins for Structure Determination using Lipidic Mesophases

Published on: November 21, 2010

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抗结核药物向物MmpL3的晶体结构

Bing Zhang1, Jun Li2, Xiaolin Yang1

  • 1Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China; CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, 200031, China; University of Chinese Academy of Sciences, Beijing, 100101, China.

Cell
|January 26, 2019
PubMed
概括

新的研究揭示了Mycobacterium结核病膜蛋白Large 3 (MmpL3) 的晶体结构及其与结核病药物候选物的复合物. 这种结构洞察对于开发针对MmpL3的新型结核病治疗至关重要.

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