在冠心病患者中对素反应多态心室慢心
Sami Viskin1, Ehud Chorin1, Dana Viskin1
1Tel Aviv Sourasky Medical Center and Sackler School of Medicine, Tel Aviv University, Israel (S.V., E.C., D.V., A. Hochstadt, A. Halkin, O.T-B., O.H., B.B., R.R.).
Circulation
|January 31, 2019
概括
在其他药物失效时,素有效治疗冠心动脉疾病患者的多态心室低心率 (VT). 在患有心律失常风暴的患者中,这种素治疗可以预防复发性静脉瘤并改善存活率.
科学领域:
- 心脏病学
- 电生理学
- 药理学
背景情况:
- 在非结构性心脏病和急性心肌梗塞中,已知多态心室低心率 (VT) 没有QT延长.
- 在没有急性缺血的冠状动脉疾病 (CAD) 中,它的发生程度不太清楚.
研究的目的:
- 在冠状动脉疾病患者中研究多态静脉瘤.
- 评估这种特定患者群体的治疗策略和结果.
主要方法:
- 在心肌梗塞或心血管复苏后,对43名多态静脉瘤患者进行了回顾性研究.
- 对静脉动触发剂,心律失常风暴的发生和对抗心律失常疗法的反应,包括素和阿米奥达龙的分析.
主要成果:
- 多态静脉动脉事件是由短合外引发的.
- 在53%的患者中发生了不律性风暴,这些风暴对常规疗法不耐药,但对素有反应.
- 在所有接受治疗的患者中,素治疗导致生存,没有长期复发.
结论:
- 在其他抗心律障碍药物失效的患者中,素有效治疗严重的多态静脉瘤和心律障碍风暴.
- 在这群人群中,用胺治疗显著改善了结果,并防止了复发.
相关概念视频
Anatomy of the Heart
119.7K
The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
119.7K
Coronary Artery Disease I: Introduction
1.1K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.1K
Coronary Artery Disease II: Pathophysiology
426
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
426
Coronary Artery Disease V: Interprofessional Care
267
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
267
Rheumatic Heart Disease I: Introduction
518
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
518
Coronary Artery Disease III: Clinical Manifestations
368
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
368


