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相关概念视频

Nucleic acids02:43

Nucleic acids

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Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
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Nucleic Acids02:43

Nucleic Acids

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Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes,...
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Polyprotic Acids03:38

Polyprotic Acids

31.9K
Acids are classified by the number of protons per molecule that they can give up in a reaction. Acids such as HCl, HNO3, and HCN that contain one ionizable hydrogen atom in each molecule are called monoprotic acids. Their reactions with water are:
31.9K
Amino acids03:42

Amino acids

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Amino acids are the monomers that comprise proteins. Each amino acid has the same fundamental structure, which consists of a central carbon atom, or the alpha (α) carbon, bonded to an amino group (NH2), a carboxyl group (COOH), and to a hydrogen atom. Every amino acid also has another atom or group of atoms bonded to the central atom known as the R group. There are 20 common amino acids present in proteins, each with a different R group. Variation in the amino acid sequence is responsible for...
105.3K
Mixtures of Acids03:27

Mixtures of Acids

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The pH of a solution containing an acid can be determined using its acid dissociation constant and its initial concentration. If a solution contains two different acids, then its pH can be determined using one of several methods depending upon the relative strength of the acids and their dissociation constants.
A Mixture of a Strong Acid and a Weak Acid
In a mixture of a strong acid and a weak acid, the strong acid dissociates completely and becomes a source of almost all the hydronium ions...
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Titration of a Polyprotic Acid02:08

Titration of a Polyprotic Acid

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A polyprotic acid contains more than one ionizable hydrogen and undergoes a stepwise ionization process.  If the acid dissociation constants of the ionizable protons differ sufficiently from each other, then the titration curve for such polyprotic acid generates a distinct equivalence point for each of its ionizable hydrogens. Therefore, titration of a diprotic acid results in the formation of two equivalence points, whereas the titration of a triprotic acid results in the formation of three...
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Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
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酸触发,酸生成和自我放大可降解的聚合物

Kali A Miller, Ephraim G Morado, Shampa R Samanta

    Journal of the American Chemical Society
    |January 31, 2019
    PubMed
    概括

    一种新的聚合物设计使用可裂变的单元, 这种自放大可降解聚合物技术为先进的材料应用提供了可控的分解和剂量释放.

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    科学领域:

    • 聚合物化学
    • 材料科学
    • 有机化学

    背景情况:

    • 酸催化水解是一种常见的化学反应.
    • 聚合物的可控降解对于各种应用至关重要.
    • 现有的可降解聚合物可能缺乏可调节或放大降解率.

    研究的目的:

    • 引入一种用于聚合物降解的新型可切割装置.
    • 开发一种新的自我放大可降解聚合物.
    • 研究酸催化降解机制和动力学.

    主要方法:

    • 合成含有3-乙部分的聚合物.
    • 用酸催化水解实验来研究降解.
    • 降解过程的动态分析和速度放大.

    主要成果:

    • 在酸催化过程中,3-乙部分有效释放HI和烯酸.
    • 这种单元的聚合物表现出酸增强的西格形降解特征.
    • 降解速度显著加快, 实现触发响应行为.

    结论:

    • 3-乙部分提供了一个简单但有效的聚合物降解触发器.
    • 这种新型的自我放大可降解聚合物显示出可调节和加速的分解.
    • 这些发现为具有可控降解和释放性质的先进材料开辟了道路.